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The lack of studies means dosing protocols are speculative, side effect profiles unknown, and risks potentially severe - particularly gastroparesis from combined extreme gastric slowing
Most people notice improvements in joint comfort and mobility within 24 weeks
They are also less likely to be affected by continuing weight loss as compared to hyaluronic acid, which gets metabolised much quicker
Setting realistic expectations is crucial, as weight loss is a gradual journey
Front Cell Neurosci 17:1101379
Consult your physician before use if pregnant or lactating
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